Our Team

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Professor John Rasko

Program Leader

Professor John Rasko AO is a clinical hematologist, pathologist and scientist with an internationally renowned track record in gene and stem cell therapy, experimental haematology and molecular biology. He leads the Gene and Stem Cell Therapy Program at The Centenary Institute and is Head, Department of Cell & Molecular Therapies, Royal Prince Alfred Hospital.

Dr. Chuck Bailey Head, Cancer & Gene Regulation

Dr. Chuck Bailey

Head, Cancer & Gene Regulation

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Past Experience: I trained as a molecular and cellular biologist (PhD, CRC for Biopharmaceutical Research, UNSW) and have 20 years’ experience in studying molecular mechanisms of genetic disease and cancer. In 2001, I joined the Gene and Stem Cell Therapy Program headed by Prof Rasko studying the molecular genetics of human amino acid transporter disorders. In 2007, I was appointed Senior Research Officer, where I began studying the role of transcription factors in cancer causation.
Current Research: I currently lead the Cancer & Gene Regulation Lab. Our aim is understanding fundamental gene regulatory mechanisms in normal biology and applying this knowledge to elucidating aberrant transcription factor function in cancer. With a particular focus on the chromatin organising protein CTCF, and its paralogue BORIS, I exam gene regulatory circuitry and protein interaction networks that are essential in cancer.
Fun Fact: I grew up in the Country Music Capital of Australia - Yeehah!
Contact: c.bailey@centenary.org.au
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A/Prof. Ulf Schmitz  Head, Computational BioMedicine

A/Prof. Ulf Schmitz

Head, Computational BioMedicine

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Past Experience: 2018 to date - Associate Faculty, Centenary Institute, University of Sydney
2018 to date - Senior Research Officer, Gene & Stem Cell Therapy Program, Centenary Institute
2017 to date - Honorary Adjunct Professor, Chhattisgarh Swami Vivekanand Technical University (CSVTU) in Bhilai, India. Association as Honorary Adjunct Professor is to strengthen cooperation and provide support to the CSVTU for setting up a center of excellence in Systems Medicine.
2016 to date - Conjoint Senior Lecturer, Faculty of Medicine & Health, University of Sydney (2nd for impact, THE Impact rankings 2020)
2015 to 2017 - Research Officer, Gene & Stem Cell Therapy Program, Centenary Institute
2003 to 2015 - Bioinformatician and Systems Engineer, Department of Systems Biology & Bioinformatics, University of Rostock, Germany
Current Research: I am a computational biologist with training in bioinformatics and systems biology and currently the head of the Computational BioMedicine Lab. My research interests focus on computational RNA biology and systems medicine. I develop integrative workflows, databases, and software tools for the analysis of gene regulation in cancer.
Fun Fact: I've been an actor in a Bollywood movie
Contact: u.schmitz@centenary.org.au
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Follow on Twitter X @ulfschmitz

Dr. Dannel YeoResearch Officer

Dr. Dannel Yeo

Research Officer

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Past Experience: I received my PhD from the University of Melbourne in 2017. I then undertook a postdoctoral position at the University of Melbourne Centre for Cancer Research where I generated and utilised 3D culture organoids from pancreatic cancer patients for precision and personalised medicine.
Current Research: I now lead the Li Ka Shing Cell and Gene Therapy Initiative Group undertaking a clinical trial in cellular immunotherapy for pancreatic cancer and investigates the clinical application of liquid biopsies in cancer.
Fun Fact: When not in the lab, you can find me on the court playing badminton or at the park playing with my dog, Sammy.
Contact: d.yeo@centenary.org.au
Follow on twitter X @yeo_dannel

Dr. Bijay Dhungel Research Officer

Dr. Bijay Dhungel

Research Officer

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Past Experience: I did my B.Tech in India before moving to Finland for MSc. I then joined the University of Queensland for my PhD which was focused on designing targeted gene therapeutic platforms for hepatocellular carcinoma based on AAV-derived vectors.
Current Research: In the Rasko lab, I aim to devise novel strategies to enhance gene therapy using AAV-based vectors. One strategy to achieve this goal is to manipulate the process of AAV transduction and vector-hostminteractions. I am currently using CRISPR-based genome-wide screens in different cell types to identify AAV-related host factors. Our ultimate goal is to modulate these host factors to increase the efficiency of AAV-mediated gene transfer.
Fun Fact: I used to be a semi-professional musician
Contact: b.dhungel@centenary.org.au
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Follow on Twitter X @dhungel_bijay

Dr. Mehdi Sharifi Tabar Research Officer

Dr. Mehdi Sharifi Tabar

Research Officer

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Past Experience: I did my B.SC and M.SC in Iran in the field of biology and protein chemistry in 2008. Then I worked as a Research Assistant for about seven years in Royan Institute for Stem Cell Biology and Technology. In 2015 I joined Prof Joel Mackay lab at the University of Sydney to do my PhD investigating the structure and function of the NuRD complex.
Current Research: I am currently studying the Protein-Protein Interaction (PPI) network of CTCF and its paralogue CTCFL using a combination of pulldown followed by mass spectrometry and Co-IP. The goal is to explain the molecular mechanisms underlying cancer pathogenesis and to identify potential molecular targets for therapy. We are interested in understanding proteins and protein complexes that regulate chromatin epigenetic modifications, and transcriptional and post-transcriptional gene expression regulation. To address biological questions, we use a range of proteomics, epi-proteomics (study of histone and non-histone proteins posttranslational modification), molecular & cell Biology, biochemical assays and genetic manipulation of model cell lines using CRISPR/Cas9 technology. We also employ a multidisciplinary approach that includes the application of multiple next generation sequencing applications (e.g., RNA-seq, and ChIP-seq) and Mass spectrometry-based proteomics.
Fun Fact: I am forgetful “sometimes” and terrible with names!
Contact: m.tabar@centenary.org.au
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Follow on Twitter X @mehdi40969858

Dr. Carl PowerEditorial Research Officer

Dr. Carl Power

Editorial Research Officer

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Past Experience: I have a Bachelor of Arts, Communication (University of Technology, Sydney) and PhD in Philosophy (University of Sydney). I have taught in these areas at university and have worked as the Editorial Coordinator of the journal Labour History.
Current Research: As an Editorial Research Officer within the Gene and Stem Cell Therapy program, my job is to research and write about the science, history and ethics of regenerative medicine.
Fun Fact: I’m very interested in the many ways that “life” has been understood throughout the ages, from the earliest creation myths to the latest fantasies of the post-human future.
Contact: c.power@centenary.org.au

Dr. Chirag Parsania

Research Officer

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Past Experience: I did my M.Sc. in bioinformatics from Savitribai Phule Pune University formerly known as University of Pune. Post M.Sc. I worked as Bioinformatics Analyst in a genomics company in India for 1.5 years. I then moved to the University of Macau to start my Ph.D which was mainly focused on tools and software development to analyze fungal genomics data and to understand transcription regulation in pathogenic fungi Candida glabrata. I joined Gene and Stem Cell Therapy Group at the Centenary Institute as a Postdoc – Bioinformatics Software Engineer, Computational Biologist in April – 2021.
Current Research: Implementing Bioinformatics approach to understand intron retention (IR) and microRNA (miRNA) mediated post transcriptional gene regulatory control focusing on cancer.
Fun Fact: I like reading balance sheets of companies. If I wasn’t bioinformatician, I would have become full time stock trader. Besides that, I enjoy driving, cooking and photography.
Contact: : c.parsania@centenary.org.au
Follow on Twitter X @ChiragParsania

Anna Leach
Clinical Trials Coordinator

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Past Experience: I have spent the past decade working in cancer clinical trials/research with a particularly strong focus on immuno/chemotherapy and in aseptic laboratories. I completed a Bachelor of Health Science in Biochemistry and Molecular Biology in 2013 and two post graduate certificates; first in Health Services Management (2017) and more recently in Infectious Disease Prevention and Control in Health (2021).
Current Research: I am currently the Clinical Research Coordinator for the La Ki Shing Cell and Gene Therapy Group working on the early detection and isolation of circulating tumour cells (CTCs) in cancer patients.
Fun Fact: I like to relax by reading (or watching) a psychological thriller or horror book (or movie) or a true crime podcast/docuseries.
Contact: a.leach@centenary.org.au

Cynthia MetierreResearch Assistant

Cynthia Metierre

Research Assistant

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Past Experience: Graduated from BBiomedSc (Hons) at the University of Technology, Sydney. I joined the Rasko Lab as a research assistant in 2002.
Current Research: My expertise is in molecular biology and my main focus is on genetic mutations in transcription factors that may cause cancer.
Fun Fact: I love baking and if I wasn't a scientist, I would want to be a pastry chef.
Contact: c.metierre@centenary.org.au

Julie FengResearch Assistant

Julie Feng

Research Assistant

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Past Experience: Graduated from UNSW, BSc (Advance)
Current Research: I study the chromatin and protein interactions of cancer cells
Fun Fact: I'm an avid kendo practitioner and represented Australia at the World Kendo Championships
Contact: j.feng@centenary.org.au

Rajini Nagarajah  Research Assistant

Rajini Nagarajah

Research Assistant

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Past Experience: I did my BSc. and MSc. in Biochemistry at Lincoln University, New Zealand. I moved to Singapore and worked as a laboratory officer in the Department of Pharmacology at the National University of Singapore. I then came to Australia and have been a research assistant at The Brain and Mind Research Institute, Woolcock Medical Research Institute and the University of Sydney Developmental and System Neuroscience, School of Medical Sciences/Physiology.
Research Interests: I contribute to and am involved in research projects in areas of cancer with expertise in animal handling.
Fun Fact: I love to collect magnets from every city as I travel around the world! I have nearly 2500 magnets on my magnetic wall. I am in the process of creating a world map with them.
Contact: r.nagarajah@centenary.org.au

Althea BastianResearch Assistant

Althea Bastian

Research Assistant

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Past Experience: Studied a Bachelor of Forensic Biology in Biomedical Science at UTS and completed an Honours research project at the Kolling Institute investigating telomerase regulation in thyroid cancer.
Current Research: We are looking at the detection and isolation of circulating tumour cells from cancer patients, particularly pancreatic cancer, and how they can inform cancer management and treatment.
Fun Fact: I keep a variety of tropical fish and shrimp.
Contact: a.bastian@centenary.org.au

Heidi StraussResearch Assistant

Heidi Strauss

Research Assistant

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Past Experience: - Master of Science in Tissue Engineering and Regenerative Medicine @ the University of Applied Sciences Technikum Wien, Vienna, Austria (2016-2019)
- Master thesis placement at the Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Vienna, Austria (2018)
- Bachelor of Medical & Health Sciences (minor in International studies) @ the University of Wollongong (2011-2014)
- 1 year of International exchange at the University of Oslo, Norway (2013)
Current Research: Circulating tumour cells in pancreatic and lung cancer
Fun Fact: - Swims, cycles, runs and eats in my free time
- Marathoner and half an IRON(wo)MAN
- Cat mama
Contact: h.strauss@centenary.org.au

Joseph Vitale
Research Assistant

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Past Experience: Bachelor of Science (Biotechnology) at the University of Technology Sydney. Honours in Applied Medical Science at CMRI Westmead through the University of Sydney.
Current Research: I am working on strategies to increase the transduction efficiency of AAV vectors into host cells to enhance the effectiveness of AAV-based gene therapies.
Fun Fact: I was born on Friday the 13th.
Contact: j.vitale@centenary.org.au

Oliver Liang

PhD Student

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Past Experience: Bachelor of Science (Honours) (Advanced) in immunology and medicinal chemistry at the University of Sydney, former summer scholar and Honours student in the Rasko Lab
Current Research: Having completed my Honours project in the Rasko Lab (fun times!) looking at the biology of mesothelin and optimising mesothelin-targeted CAR-T cell therapy for pancreatic cancer, my current PhD project focuses on improving the efficacy and immunocompatibility of anti-mesothelin CAR-T cell therapy for pancreatic cancer. Specifically, I will test if different delivery methods, immune cell types, and manufacturing designs can enhance the responses of this novel cancer immunotherapy in vitro and in vivo.
Fun Fact: I love ants (and insects in general)!
Contact: o.liang@centenary.org.au
Follow on Twitter X @OliverLiang15

Dr. Prajwol Shrestha

PhD Student

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Past Experience: I am a fellow of the Royal Australasian College of Physicians and a medical oncologist at Calvary Mater Newcastle. I undertook a phase 1 clinical trial fellowship at Chris O’Brien Lifehouse in 2021 after completing medical oncology training at Calvary Mater Newcastle and Gosford Hospital. I completed my basic physician training at Nepean Hospital and received my primary medical degree from Manipal College of Medical Sciences, Nepal. Besides lung cancer, my other special interests include gastrointestinal and genitourinary cancers, along with critical care planning for oncology patients. Besides being involved in multiple phase 1 to 3 clinical trials, my past research involvement includes immunotherapy in advanced cutaneous SCCs, immunotherapy scheduling and associated toxicities, outcomes of advanced lung cancer patients admitted to ICU and resected colorectal liver metastases.
Current Research: In Rasko lab, I am currently undertaking a PhD in circulating tumour cells in Small cell lung cancer and working on improving the detection technique and characterisation of these rare cells to better guide our treatment strategy in lung cancer.
Fun Fact: In a parallel universe, I would be a Musician, Wildlife photographer, or Scuba diver.
Contact: p.shrestha@centenary.org.au

Elena Skorokhodova

Honours Student

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Past Experience: Bachelor of Science (majoring in Biochemistry and Quantitative Life Sciences) at the University of Sydney
Current Research: As a part of my Honours project, I am exploring the interactome of ZNF185 to elucidate its function in pancreatic cancer.
Fun Fact: Passionate about protection of human rights.
Contact: e.skorokhodova@centenary.org.au

Ruby Hu

Honours Student

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Past Experience: Bachelor of Science (Biochemistry and Molecular Biology, Immunology and Pathology) - at the University of Sydney.
Current Research: My honours project is doing CAR T cell therapy on pancreatic ductal adenocarcinoma (PDAC) patients drived organoids. In this project, I investigate the CAR T cytotoxicity and avidity in different antigen density, and results will be validated into in vivo mouse model.
Fun Fact: Science & detective fictions fan and I love spending my spare time on watching sci-fi movies.
Contact: r.hu@centenary.org.au

Harrison Bazley

Honours Student

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Past Experience: Bachelor of Science (Medical science) (Genetics and Genomics) at the University of Sydney.
Current Research: I am currently completing an honours project titled 'Modulating AAV host factors to improve gene therapy efficacy'.
Fun Fact: I love ants (and insects in general)!
Contact: h.bazley@centenary.org.au
Follow on Twitter X @HarrisonBazley

Dr. Qian Peter SuVisiting Scientist

Dr. Qian Peter Su

Visiting Scientist

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Past Experience: In 2017, I received my PhD in Biophysics supervised by Profs Xiaoliang Sunney Xie and Yujie Sun from Biodynamic Optical Imaging Centre (BIOPIC) in Peking University (PKU) with the honour of “Outstanding Graduate Student of the Beijing City”. In 2012, I took an overseas exchange scholarship and received mentorship on the instrumentation of super-resolution microscopy in Profs Xiaoliang Sunney Xie and Xiaowei Zhuang’s labs at Harvard University. I received my B.Eng. in Bio-Engineering supervised by Prof Linhong Deng in 2011 from College of Bioengineering, Chongqing University.
Current Research: I am currently an Emerging Leadership 1 Fellow (2020-25) of NHMRC and Postdoctoral Fellow (2020-22, co-fund) of National Heart Foundation. I am also a Lecturer (faculty member) and Group Leader of the Laboratory of Quantitative Imaging At Nanoscale with SUper-resolution (Qian Su Lab) in the School of Biomedical Engineering at the University of Technology Sydney (UTS). I'm also a part-time visiting scientist at Heart Research Institute and Centenary Institute at the University of Sydney. My research focuses on establishing an “Imaging Profiling Platform for Cardiovascular Disease” supported by the Volumetric Imaging Facility (VIF), of which I am the facility manager and key operator.
Fun Fact: I do trans-scale photographer for scenery, portrait, small animal, tissue, single cell and single molecule.
Contact: Qian.Su@uts.edu.au or visit www.qiansulab.com
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Follow on Twitter X @QianPeterSu

Zoe Marks

Visiting Scientist

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Past Experience: I am an early-career clinician-scientist. I received my Bachelor of Medicine/Bachelor of Surgery (MBBS) from Monash University in 2019. During medical training, I undertook a Bachelor of Medical Science (BMedSci) and then PhD at the Hudson Institute of Medical Research, VIC, investigating type I interferon signalling in breast and ovarian cancer. I subsequently worked as a Clinical Research Fellow in the biotechnology industry in Boston, MA, developing novel therapies targeting inflammation and cancer.
Current Research: I am currently a medical trainee in the Department of Cell & Molecular Therapies (CMT) at the Royal Prince Alfred Hospital where I’m involved in the provision of cell & gene therapies both commercially and in clinical trials. In conjunction, I am a visiting researcher in the Gene and Stem Cell Therapy Laboratory at the Centenary Institute investigating innate immunology and cancer.
Fun Fact: I am an avid op-shopper and amateur sketch artist. My dog, Leo, thinks I’m a MasterChef.
Contact: z.marks@centenary.org.au
Follow on Twitter X @ZoeMarks16